Humman Cloning Essay Example

Humman Cloning Essay * INTRODUCTION: The world of science and the public at large were both shocked and fascinated by the announcement in the journal Nature by Ian Wilmut and his colleagues that they had successfully cloned a sheep from a single cell of an adult sheep (Wilmut 1997). Scientists were in part surprised, because many had believed that after the very early stage of embryo development at which differentiation of cell function begins to take place, it would not be possible to achieve cloning of an adult mammal by nuclear transfer. In this process, the nucleus from the cell of an adult mammal is inserted into an ennucleated ovum, and the resulting embryo develops following the complete genetic code of the mammal from which the inserted nucleus was obtained. But some scientists and much of the public were troubled or apparently even horrified at the prospect that if adult mammals such as sheep could be cloned, then cloning of adult humans by the sameprocess would likely be possible as well. Of course, the process is far from perfected even with sheep— it took 276 failures by Wilmut and his colleagues to produce Dolly, their one success. Whether the process can be successfully replicated in other mammals, much less in humans, is not now known. But those who were horrified at the prospect of human cloning were not assuaged by the fact that the science with humans is not yet there, for it looked to them now perilously close. The response of most scientific and political leaders to the prospect of human cloning, indeed of Dr. Wilmut as well, was of immediate and strong condemnation. We will write a custom essay sample on Humman Cloning specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Humman Cloning specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Humman Cloning specifically for you FOR ONLY $16.38 $13.9/page Hire Writer In the United States, President Clinton immediately banned federal financing of human cloning research and asked privately funded scientists to halt such work until the newly formed National Bioethics Advisory Commission could review the â€Å"troubling† ethical and legal implications. The Director-General of the World Health Organization (WHO) characterized human cloning as â€Å"ethically unacceptable as it would violate some of the basic principles which govern medically assisted reproduction. These include respect for the dignity of the human being and the protection of the security of human genetic material† (WHO 1997). Around the world similar immediate condemnation was heard, as human cloning was called a violation of human rights and human dignity. Even before Wilmut’s announcement, human cloning had been made illegal in nearly all countries in Europe and had been condemned by the Council of Europe (Council of Europe 1986). A few more cautious voices were heard, both suggesting some possible benefits from the use of human cloning in limited circumstances and questioning its too quick prohibition, but they were a clear minority. In the popular media, nightmare scenarios of laboratory mistakes resulting in monsters, the cloning of armies of Hitlers, the exploitative use of cloning for totalitarian ends as in Huxley’s Brave New World, and the murderous replicas of the film Blade Runner, all fed the public controversy and uneasiness. A striking feature of these early responses was that their strength and intensity seemed to far outrun the arguments and reasons offered in support of them— they seemed often to be â€Å"gut level† emotional reactions rather than considered reflections on the issues. Such reactions should not be simply dismissed, both because they may point us to important considerations otherwise missed and not easily articulated, and because they often have a major impact on public policy. But the formation of public policy should not ignore the moral reasons and arguments that bear on the practice of human cloning— these must be articulated inE-4 order to understand and inform people’s more immediate emotional responses. This paper is an effort to articulate, and to evaluate critically, the main moral considerations and arguments for and against human cloning. Though many people’s religious beliefs inform their views on human cloning, and it is often difficult to separate religious from secular positions, I shall restrict myself to arguments and reasons that can be given a clear secular formulation and will ignore explicitly religious positions and arguments pro or con. I shall also be concerned principally with cloning by nuclear transfer, which permits cloning of an adult, not cloning by embryo splitting, although some of the issues apply to both (Cohen and Tomkin 1994). I begin by noting that on each side of the issue there are two distinct kinds of moral arguments brought forward. On the one hand, some opponents claim that human cloning would violate fundamental moral or human rights, while some proponents argue that its prohibition would violate such rights. On the other hand, both opponents and proponents also cite the likely harms and benefits, both to individuals and to society, of the practice. While moral and even human rights need not be understood as bsolute, that is, as morally requiring people to respect them no matter how great the costs or bad consequences of doing so, they do place moralrestrictions on permissible actions that appeal to a mere balance of benefits over harms. For example, the rights of human subjects in research must be respected even if the result is that some potentially beneficial research is made more difficult or cannot be done, and the right of free expression prohibits the silencing of unpopular or even abhorrent views; in Ronald Dworkin’s striking formulation, rights trump utility (Dworkin 1978). I shall take up both the moral rights implicated in human cloning, as well as its more likely significant benefits and harms, because none of the rights as applied to human cloning is sufficiently uncontroversial and strong to settle decisively the morality of the practice one way or the other. But because of their strong moral force, the assessment of the moral rights putatively at stake is especially important. A further complexity here is that it is sometimes controversial whether a particular consideration is merely a matter of benefits and harms, or is instead a matter of moral or human rights. I shall begin with the arguments in support of permitting human cloning, although with no implication that it is the stronger or weaker position * The possibility of human cloning, raised when Scottish scientists at Roslin Institute created the much-celebrated sheep Dolly (Nature  385,  810-13, 1997), aroused worldwide interest and concern because of its scientific and ethical implications. The feat, cited by  Science  magazine as the breakthrough of 1997, also generated uncertainty over the meaning of cloning an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. Historical Background: The history of human cloning human cloning is undoubtedly one of the most fascinating chapters of our lives. Essential question to be discussed to understand the ramifications of human cloning is when human life begins? C. Ward Kischer, a famous American embryologists, wrote in a recent article: Since 1973 when Roe vs. Wade was wo n there were many socio-legal issues related to human embryo. Abortion, fertilization in vitro research on human embryos, research on stem cells, cloning and genetic engineering are substantive issues of human embryology†. The answer is clear embryology that life begins at fertilization of the egg by a sperm (sexual reproduction) or if the SCNT cloning, implantation and activation when the donor somatic cell nucleus into an egg recipient (asexual reproduction). (6) Although non-mammalian cloning was achieved in 1952, mankind had to wait another 44 years until he was finally cloned the first mammal. The first cloned mammal, Dolly the sheep was born on July 5, 1996. In this fascinating history of cloning, there has been a major setback in 2003 when Dolly died at the age of 6 years. Death of the first cloned mammal, was followed by a lively debate related issues / ethical aspects of cloning, debate that continues today. Besides the successful attempts to clone the different species of animals, XX century was marked by several important moments in the development of the genealogy. Deciphering the success of DNA code in 1968 came as an enormous progress around much desired human clone. With nearly 20 years later, by 1988 the human genome, that genome Homosapiens stored in 23 pairs of chromosomes has been released. As things were headed becoming better by the appearance of a human clone, a major problem has become human cloning prohibition act in 2009, which has labeled as cloning illegal, immoral, not unethical activity. Since 2009, human cloning is illegal in 23 countries. So far, experiments were undertaken with five species of animals and the high rate of failure has given rise to many questions about human cloning success. Only 1% of animal cloning made so far have had a positive result, but most of them have suffered serious disorders. The conclusion of experts is that the current level of technology, human cloning is very dangerous. I discussed two types of human cloning: therapeutic cloning and reproductive cloning. Therapeutic cloning involves cloning cells from an adult for medicinal use and is an active research area, while reproductive cloning would involve the creation of human clones. Therapeutic cloning could provide unique ways to cure diseases until now considered incurable: diabetes, Parkinsons, Alzheimers, heart disease. (1) The third type of cloning called replacement cloning is a possibility in theory and would be a combination of therapeutic cloning and reproductive cloning. Higher probability of achieving a therapeutic cloning is more accessible in terms of technique, but also less morally problematic. * Statement Of The Problem: * What is cloning? Are there different types of cloning * How can cloning technologies be used? * What Animal Haved Been Cloned ? * Can organs be cloned for use in transplants? * What are the risks of cloning? * Should humans be cloned? * How Human Cloning Will Work Cause And Effect: Ethics Ethical issues of human cloning have become an important issue in recent years. Many ethical arguments against human cloning are based on misconceptions. Many people think that these clones will have the same characteristics / personalities as the person cloned. Although clone and cloned individual have the same genes, traits and personalities are different. People think that a clone is physically identical to the donor and her behavior, but this is not true because although there is a physical identity, living environment shapes an individuals ongoing behavior and psychology. Many people believe that cloning will lead to loss of individuality eventually, but people have their own personality cloned which personality is similar to those in which they were created. Lawrence Nelson, associate professor of philosophy at UCS, said that embryos can be used for research if: the purpose of research can not be achieved by other methods;    the embryos have reached more than 14-18 days of development;    those who use forbid you to consider or treat as personal property. One of the most serious problems of cloning of human embryos for therapeutic purposes, is that with harvesting stem cells, the embryo is formed by cloning practical killed. We can not reduce the existence of a human embryo to a cell as long as after both science and teaching of the Church, the human embryo is a carrier of life. 8) For a few years, the legalization of human cloning is in the center of global debate, which was also attended not only scientists but also politicians, philosophers, theologians, psychologists. For example, American Association of Pro Life Obstetricians and Gynecologists (AAPLOG) has spoken out against cloning, drawing attention that some business people might think of trading a human life. (4) What is harder is that it could reach the reproduction of living people without them knowing, to be involved in this process or to give consent. Questions appeared on the social status of any clone. What will be their status in society? In the U. S. House of Representatives issued a ruling that human cloning is illegal, but the Senate has yet to rule on the matter. The opinions are still leaning toward accepting only therapeutic cloning. Legalization of therapeutic cloning has been proposed as the only way to investigate, the chances of success, the basic criterion for funding such programs as the primary objective should be finding cures for incurable diseases. A coalition of states, including Spain, Italy, Philippines, USA, Costa Rica and the Holy Land have tried to expand the debate on all forms of human cloning, noting that in their view, therapeutic cloning violates human dignity. Costa Rica proposed the adoption of an international convention to combat any form of cloning. Australia has banned human cloning in December 2006, but therapeutic cloning is now legal in some parts of Australia. European Union European Convention on Human Rights prohibits human cloning in an additional protocol, but the protocol has been ratified only by Greece, Spain and Portugal. England The British government introduced legislation to allow therapeutic cloning in a debate on January 14, 2001. Hope that parliament will pass the law was prohibitive. Roman Catholic Church under Pope Benedict XVI has condemned the practice of human cloning, saying it represents a grave offense against human dignity and equality among the people. Human cloning is prohibited in Islam at the Tenth Conference in Jeddah. Saudi Arabia has decided on June 28, 1997-July 3, 1997 as the beginning of human cloning is haraam (forbidden by the faith-sin). Jesse Rainbow explain why there is an aversion to human cloning a clone would not be a real person cloning is playing the God cloning is not natural mention in closing some of the conditions proposed in a provisional list yet, so research on therapeutic human cloning (reproductive one is illegal) to proceed lawfully: it is necessary for embryos to be used only in the early stages of their development, without being allowed to grow further, all programs research must be supervised by government organizations dealing with fertilization and genetic techniques, various research programs will receive funding and approval only if it is scientifically demonstrated that there is no other way of obtaining the same results conventional, will not be permitted to research on human genetic material can be combined with that of animals, there must be a permanent state of public information on research undertaken and to be postulated that the limitations may be required to report the experiences and suffering of animals used for human benefit. (5)

Use the STAR Method to answer any interview question

Use the STAR Method to answer any interview question It’s interview day. You’ve worked on your handshake, your eye contact, your head-to-toe professional outfit. You know your resume backwards and forwards, and you’ve reviewed the job description so many times you can practically see it when you close your eyes. So, you’re ready. And then in the interview, you get a question you weren’t necessarily expecting: â€Å"Tell me about a time when you†¦Ã¢â‚¬  Argh, the dreaded behavioral questions. Now what? First, don’t panic. You can answer any question an interviewer throws your way, without grinding the whole thing to a halt. It’s as simple as being a STAR.What’s the STAR Method  and  how  do  you  use  it?STAR is a method you can use to frame an answer quickly and efficiently. It’s an acronym for:Situation: Where/when did this example take place?Task: What was your level of responsibility in this example?Action: What steps did you take?Result: What was the outcome, and what did you learn or achieve?Let’s break down some strategies for using the STAR method in your next and future interviews.Find the right exampleUnless something comes to mind right away, this can be the hardest part. But think of it this way: the question is likely to be a situation that is tied to something on your resume or a task in the job description, so this is something you can think about in advance, even if you don’t know what will be asked specifically. Ahead of the interview, come up with examples or anecdotes for every experience bullet point and skill on your resume. That way, when you’re asked, â€Å"Tell me about at time you showed leadership,† you will already have a list of relevant points ready to go.Relevance is the key- you don’t want to start rambling about something that doesn’t really fit what the interviewer is asking. So the quick internal check should be, â€Å"I think this is the right story- does it answer what’s being asked?†And if you need a bit of time to think things over, say so- it’s okay to ask for a minute to think things over. â€Å"That’s a really great question; I’d like to think about it for a minute!† You don’t want your contemplation to go too long, but taking 30 seconds to gather your thoughts will lead to a better answer.Set the sceneThis doesn’t have to be an elaborate, cinematic story. However, you should be able to give a few quick details to show the interviewer what the context is for your story.I was the lead on a project, and 80% of my team had called in sick†¦We were on schedule and on budget, when the client changed his mind in the middle of the meeting†¦I took a call from an angry customer, who was not interested in hearing the company’s side of the story†¦You’ll want to make it conversational so that it doesn’t sound like you memorized a card. All you need are a few short sentences- no need to provide detailed backstory about everyone involved or a history of your employment. You want the details to be directly relevant to your story. And it’s okay to be humorous or light in your response, as long as you keep the tone professional.Talk about what you did to solve the problem or approach the issueOnce you’ve set the scene for the interviewer, talk about what you did to resolve the issue. Usually, when interviewers ask behavioral-style questions, they’re just as interested in the how as the what. And again, this doesn’t need to be a long-winded, detailed step-by-step. A few succinct bullet points about what you did in the situation will be just fine. If the interviewer has any follow-up questions, she’ll ask.Talk up your achievements- or lessons learnedWhen you’re talking about the results, don’t be afraid to talk about what you achieved- especially if it puts you in a positive light. You don’t want to come off like a braggart, but you should own your accomplishments.The project came in under budget thanks to my fix, and we broke sales records that year.Because I caught the order before it was processed, I was able to stop 5,000 widgets from being shipped accidentally. That was a great feeling.And if you picked an example that didn’t necessarily have a happy ending (because hey, sometimes that’s the only anecdote that fits), be sure to talk about what you did gain from the situation.Although it was difficult   while I worked to resolve the issue, it taught me that nothing is more important than providing a superior customer experience.It was definitely a learning experience, and having worked with such a demanding client, I know I can work with anyone to get the job done.Like with your other STAR points, a couple of sentences should be all you need to summarize and wrap up your story.Practice beforehandIf you’re not all that comfortable with storytelling, this is definitely a skill you can build before you’re in the interview hot seat. Just like with body language or your handshake, practice until it becomes second nature! Grab a trusted person who can ask you general behavioral questions, and apply the STAR method to your conversation. If you do this enough times in your everyday life, you won’t be sitting in the interview thinking, â€Å"Okay, time for S. What’s the situation?† You’ll already be searching through your mind’s archive for the relevant anecdote.   Ã‚  If you prep for interviews with the STAR method, you can tackle any question an interviewer throws your way, even if it seems like it comes out of nowhere. Quick, to-the-point answers will impress your interviewer and demonstrate that you have one of the most important skills- thinking on you r feet.

Statistical Tool for Financial Research Paper Example | Topics and Well Written Essays - 2000 words

Statistical Tool for Financial - Research Paper Example However IPOs problems affect not simply corporations but also start-up companies facing plenty of obstacles, including the cost of Compliance with Sarbanes Oxley. Modern corporate finance however unanimously points to a formidable hurdle: Portfolio executives. Considering that the timing of an IPO will be driven by company growth and market conditions, we have based our assumptions for an efficient portfolio strategy on improving capital markets with IPOs hoping to maximise their wealth. With a rapid growth of issuers' activity on the cable markets, expected to continue in the next few years, we have used Time Warner Cable unit for this case study. If Section 1 illustrates and develops the implications of a newly created portfolio detailing executive level strategic financial decisions for the following year, Section 2 is more focused on the concept of decision planning as well as on its effects in case of poor corporate governance decisions. We have based the risk-return characteris tics of our rolling portfolio investment strategy on stocks bought and held for up to one year. Although the average long-run portfolio return is low and in line with market reactions to security offer announcements, this IPO stocks appear as long-shots, securing a buy-and-hold returns of 1,000 percent. In line with average NASDAQ market capitalization our IPO firm exhibits relatively high stock turnover and low leverage, contributing to lower systematic risk exposures. To analyse the implications of these strategic decisions, we have based our assessment on globally acknowledged peer-reviewed research and theory. Our conclusions are finally presented in Section 3. 1. Newly created portfolio strategy and executive-level strategic financial decision making The acknowledgement that flipping is useful in helping to create liquidity may convince an executive team that focusing resources almost exclusively on a few late-stage assets is a wise move. Measuring value and risk at portfolio level can contribute to appropriately capture the portfolio strategic risk and induce executives dissatisfied with the current status quo to analyse if they intend to leave corporate strategic risk management and diversification completely to shareholders and markets or how an independent growth path can be possible in their high-risk business. To analyse these issues it is important to develop a structured approach that helps senior executives better understand the impact of portfolio decisions on risk and value of the corporate or therapy area level portfolios. Therefore we have based our approach on assessing a strategy of purchasing and holding successive IPO stocks receives an expected return commensurable with risk. Usually this can be achieved by crea ting different market scenarios reflecting uncertainty around the product profile and resulting in a Risk and Value plot at the portfolio level. In consideration of the above, we have assessed this portfolio by using the Markowitz two assets portfolio model. Clearly when managing a very active investment portfolio against a well-defined benchmark, the goal of the manager should be to generate a return that exceeds that of the benchmark while minimizing the portfolio's return volatility relative to the benchmark. Assuming a portfolio of assets